Structural Basis of Efficacy-Driven Ligand Selectivity at GPCRs

Nature Chem Biol 2023
Powers, A. S., Pham, V., et al.

The Clinical Candidate Xanomeline Displays a Binate Orthosteric and Allosteric Binding and Pharmacological Profile at the M4 mACHR

American College of Psychopharmacology (ACNP) Annual Meeting; 2022 December 4-7.
Burger, W., Vuckovic, Z., et al.

Muscarinic Acetylcholine Receptors for Psychotic Disorders: Bench-side to Clinic

Trends Pharmacol Sci. 2022 Dec;43(12):1098-1112.
Yohn, S., Weiden, P., et al.